The ability to explore the genome on a sub-nucleosome level promises to lead to new discoveries about how chromatin structure is linked to epigenetics ...

理化学研究所（理研）生命医科学研究センタートランスクリプトーム研究チームのアレッサンドロ・ボネッティ客員研究員、ピエロ・カルニンチチームリーダーらの研究チームは、細胞核内のRNAとゲノムDNA（クロマチン[1] ）の相互作用をゲノム全体で調べる ...

In eukaryotes, genomic DNA is stored in the nucleus as nucleosomes, interacting with a set of proteins, forming a molecular complex called chromatin. The proper folding of the chromatin structure ...

Within the realm of genetic regulation, chromatin modifications such as histone methylation and acetylation play pivotal roles in the transcriptional control of genes. Disruptions in these processes ...

The human genome is about two meters long, yet it fits inside a nucleus only ~10 micrometers in diameter. A research team led ...

Previously, linker histone H1 was thought to bind stably to nucleosomes and compact chromatin by forming an ordered, “rigid” ...