Mast cells are pivotal effectors in immune responses, acting as both sentinels and mediators in allergic and inflammatory processes. Their ability to rapidly degranulate and release a myriad of ...

MastCURe, a high-profile research consortium, has been awarded EUR1.3M in funding from the Eureka Eurostars program. The collaboration comprising Allegria Therapeutics, Cube Biotech, and the ...

Scientists at Zhejiang University have found a way to turn allergy-causing cells in the body into cancer-fighting agents, offering a new targeted approach that combines immune system activation with ...

The itching, redness and swelling of an allergic reaction are caused by mast cells — the vigilant first responders of the immune system that spring into action with histamine-filled granules in ...

Food allergies affect more than half a billion people worldwide. In severe cases, even a small bite of the wrong food can trigger anaphylaxis - a rapid, body-wide allergic reaction that can cause ...

Scientists show that prenatal stress reshapes fetal mast cells and sensory neurons, creating a fragile skin barrier that sparks early-life eczema in mice. Study: Maternal stress triggers early-life ...

Three G protein–coupled receptors, the cysteinyl leukotriene receptors 1, 2, and 3 (CysLTR1, CysLTR2, and CysLTR3), mediate the effects of the cysteinyl leukotrienes in vivo. (Each receptor has a ...

There's now another reason to love Japan's famous matcha: A study in mice suggests that the green tea powder could reduce the need to sneeze in people with nasal allergies.