The human genome is about two meters long, yet it fits inside a nucleus only ~10 micrometers in diameter. A research team led ...

First public disclosure of the chemical structure of AMX-883, an orally bioavailable, highly potent and selective DCAF16-dependent Targeted Glue™ ...

Developmental dysplasia of the hip, or DDH, is an abnormality of the hip joint that affects posture and movement. Symptoms of DDH can appear as early ...

Scientists from Skoltech and the University of Potsdam have developed a physical theory that sheds light on how molecular ...

DNA inside the nucleus is not packed as a rigid regular fiber-linker histone H1 dynamically binds and loosely "glues" ...

DNA inside the nucleus is not packed as a rigid regular fiber—linker histone H1 dynamically binds and loosely "glues" nucleosomes together, creating a ...

Previously, linker histone H1 was thought to bind stably to nucleosomes and compact chromatin by forming an ordered, “rigid” ...

Single-cell analysis fails to find a functional link between the organization of chromatin domain organization and gene activity.

Northwestern Medicine scientists have discovered that a specific long non-coding RNA activates oncogenic signaling pathways ...

A macrophage that has already fought off one infection does not return to a blank slate. It carries chemical scars, etched ...

DNA inside the nucleus is not packed as a rigid regular fiber—linker histone H1 dynamically binds and loosely "glues" ...

Developmental dysplasia of the hip (DDH) is a polygenetic disorder that increases the risk of hip osteoarthritis.